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BIAL Foundation
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TI:"Final report - Atypical visual evoked potentials in children with autism generated by both low and high spatial frequency gratings"
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DocumentFinal report - Atypical visual evoked potentials in children with autism generated by both low and high spatial frequency gratings2006

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-047
Location: Arquivo PCA - Pasta 3/2004
Title:
047 - A combined psychophysiological and electrophysiological approach to investigate low-level visual perception in autism
Duration: 2005-06 - 2006-10
Researcher(s):
Olivier Pascalis, Elizabeth Milne, David Buckley, Laurence Vigon
Institution(s): Department of Psychology, The University of Sheffield (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Poster
1 Article
Journal Cahiers de Psychologie Cognitive/ Current Psychology of Cognition
Language: eng
Author:
Pascalis, O.
Secondary author(s):
Milne, E., Buckley, D., Vigon, L.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Vision / Biopsychological problems / Childhood and adolescent disorders / Autism spectrum disorder (ASD) / Cognitive processes / Perception

Reference code: PT/FB/BL-2004-047.01
Location: Arquivo PCA - Pasta 3/2004
Title:
Final report - Atypical visual evoked potentials in children with autism generated by both low and high spatial frequency gratings
Publication year: 2006
URL:
http://www.bial.com/imagem/Bolsa%204704.pdf
Abstract/Results: RESULTS:
There are reports of atypical visual perception in individuals with autistic spectrum disorders (ASD) meaning that they perceive the world differently to typical observers. It remains unclear whether atypical perception reflects abnormality in the visual system, i.e. bottom-up processes, or in higher level cognition and information processing biases, i.e. top-down processes. The aim of this study was to investigate basic visual perception in participants with autistic spectrum disorder by measuring the visual evoked potentials elicited by simple visual stimuli in 20 children /adolescents with autistic spectrum disorder and 20 typically developing controls. We predicted, based on existing literature, that low frequencies will be specifically
atypical in autism and that high spatial frequencies may be intact. The VEP elicited by Gabor patches presented at different spatial frequencies was measured (0.5 – 8 cycles/°). We found significant differences in the VEP elicited in the two groups. Specifically, the latency to peak was faster in the children with ASD than in the controls, and the amplitude of the C1 component was reduced in the majority of children with ASD. These data provide evidence of abnormality at a very early stage of visual processing in ASD, possibly at the level of V1. The finding reported here reflects the fact that 61.2% of the participants with autism did not have a negative component in their waveforms. This lack of C1 in some participants does not appear to correlate with age, IQ, severity of symptoms (as measured by the ASQ & CARS) or behavioural performance. It is now crucial to determine if such impairment influences the development of social cognitive functions such as face processing.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Milne, E.
Secondary author(s):
Scope, A., Buckley, D., Vigon, L. , Pascalis, O.
Document type:
Final report
Number of reproductions:
1
Indexed document:
No
Keywords: Psychophysiology / Perception / Autism spectrum disorder (ASD)

Relatório final - A combined psychophysiological and electrophysiological approach to investigate low-level visual perception in autism

Relatório final - A combined psychophysiological and electrophysiological approach to investigate low-level visual perception in autism