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BIAL Foundation
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DocumentIndependent component analysis reveals atypical electroencephalographic activity during visual perception in individuals with autism2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2002
Location: Arquivo PCA - Pastas 1 a 21/2002
Title:
2002 Grants
Start date: 2003-01 - 2009-11
Dimension/support:
21 caixas de arquivo

Reference code: PT/FB/BL-2002-096
Location: Arquivo PCA - Pasta 6/2002
Title:
096 - Face processing in 3-day-olds: an electrophysiological approach
Duration: 2003-01 - 2005-02
Researcher(s):
Olivier Pascalis, de Haan Michelle, Saachi Reza
Institution(s): Department of Psychology, The University of Sheffield (UK)
Contents: Contents:
Application form
Correspondence
Financial report and expenditure documents
Progress report
Final report
Article
Language: eng
Author:
Pascalis, O.
Secondary author(s):
Haan, M., Saatchi, R.
Number of reproductions:
1
Keywords:
Psychophysiology / Developmental psychology / Brain structure and function

Reference code: PT/FB/BL-2002-096.03
Location: Arquivo PCA - Pasta 6/2002
Title:
Independent component analysis reveals atypical electroencephalographic activity during visual perception in individuals with autism
Publication year: 2009
URL:
http://www.sciencedirect.com/science/article/pii/S000632230800886X
Contents: http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=294&SID=Z1T1li1SW9lnlKPlMpq&page=1&doc=1
Abstract/Results: ABSTRACT:
BACKGROUND:
Individuals with autistic spectrum disorder (ASD) experience atypical visual perception, yet the etiology of this remains unknown. The aim of this study was to investigate the neural correlates of visual perception in individuals with and without ASD by carrying out a detailed analysis of the dynamic brain processes elicited by perception of a simple visual stimulus.
METHODS:
We investigated perception in 20 individuals with ASD and 20 control subjects with electroencephalography (EEG). Visual evoked potentials elicited by Gabor patches of varying spatial frequency and stimulus-induced changes in a- and ?-frequency bands of independent components were compared in those with and without ASD.
RESULTS:
By decomposing the EEG data into independent components, we identified several processes that contributed to the average event related potential recorded at the scalp. Differences between the ASD and control groups were found only in some of these processes. Specifically, in those components that were in or near the striate or extrastriate cortex, stimulus spatial frequency exerted a smaller effect on induced increases in a- and ?-band power, and time to peak a-band power was reduced, in the participants with ASD. Induced a-band power of components that were in or near the cingulate gyrus was increased in the participants with ASD, and the components that were in or near the parietal cortex did not differ between the two groups.
CONCLUSION:
Atypical processing is evident in individuals with ASD during perception of simple visual stimuli. The implications of these data for existing theories of atypical perception in ASD are discussed.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Milne, E.
Secondary author(s):
Scope, A., Pascalis, O., Buckley, D., Makeig, S.
Document type:
Article
Number of reproductions:
1
Reference:
Milne, E., Scope, A., Pascalis, O., Buckley, D., & Makeig, S. (2009). Independent Component Analysis Reveals Atypical Electroencephalographic Activity During Visual Perception in Individuals with Autism. Biological Psychiatry, 65(1), 22-30. https://doi.org/10.1016/j.biopsych.2008.07.017
2-year Impact Factor: 8.926|2009
Times cited: 107|2025-09-09
Indexed document: Yes
Quartile: Q1
Keywords: Alpha power / Autism / Cingulate Gyrus / Gamma power / Perception / Spatial frequency / Visual cortex

Novo ficheiro

Novo ficheiro
DocumentIndependent component analysis reveals atypical EEG activity during visual perception in individuals with autism2009

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2004
Location: Arquivo PCA - Pastas 1 a 25/2004
Title:
2004 Grants
Start date: 2005-01 - 2012-09
Dimension/support:
25 caixas de arquivo

Reference code: PT/FB/BL-2004-047
Location: Arquivo PCA - Pasta 3/2004
Title:
047 - A combined psychophysiological and electrophysiological approach to investigate low-level visual perception in autism
Duration: 2005-06 - 2006-10
Researcher(s):
Olivier Pascalis, Elizabeth Milne, David Buckley, Laurence Vigon
Institution(s): Department of Psychology, The University of Sheffield (UK)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Financial report and expenditure documents
Progress reports
Final report
Poster
1 Article
Journal Cahiers de Psychologie Cognitive/ Current Psychology of Cognition
Language: eng
Author:
Pascalis, O.
Secondary author(s):
Milne, E., Buckley, D., Vigon, L.
Number of reproductions:
1
Keywords:
Psychophysiology / Body structure and function / Vision / Biopsychological problems / Childhood and adolescent disorders / Autism spectrum disorder (ASD) / Cognitive processes / Perception

Reference code: PT/FB/BL-2004-047.02
Location: Arquivo PCA - Pasta 3/2004
Title:
Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism
Publication year: 2009
URL:
http://www.biologicalpsychiatryjournal.com/article/S0006-3223(08)00886-X/abstract
Abstract/Results: ABSTRACT:
BACKGROUND:
Individuals with autistic spectrum disorder (ASD) experience atypical visual perception, yet the etiology of this remains unknown. The aim of this study was to investigate the neural correlates of visual perception in individuals with and without ASD by carrying out a detailed analysis of the dynamic brain processes elicited by perception of a simple visual stimulus.
METHODS:
We investigated perception in 20 individuals with ASD and 20 control subjects with electroencephalograph(EEG). Visual evoked potentials elicited by Gabor patches of varying spatial frequency and stimulus-induced changes in a- and ?-frequency bands of independent components were compared in those with and without ASD.
RESULTS:
By decomposing the EEG data into independent components, we identified several processes that contributed to the average event related potential recorded at the scalp. Differences between the ASD and control groups were found only in some of these processes. Specifically, in those components that were in or near the striate or extrastriate cortex, stimulus spatial frequency exerted a smaller effect on induced increases in a- and ?-band power, and time to peak a-band power was reduced, in the participants with ASD. Induced a-band power of components that were in or near the cingulate gyrus was increased in the participants with ASD, and the components that were in or near the parietal cortex did not differ between the two groups.
CONCLUSIONS:
Atypical processing is evident in individuals with ASD during perception of simple visual stimuli. The implications of these data for existing theories of atypical perception in ASD are discussed.
Accessibility: Document exists in file
Copyright/Reproduction:
By permission
Language:
eng
Author:
Milne, E.
Secondary author(s):
Scope, A., Pascalis, O., Buckley, D., Makeig, S.
Document type:
Article
Number of reproductions:
1
Reference:
Milne, E., Scope, A., Pascalis, O., Buckley, D., & Makeig, S. (2009). Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism. Biological Psychiatry, 65(1), 22-30. https://doi.org/10.1016/j.biopsych.2008.07.017
2-year Impact Factor: 8.926|2009
Times cited: 107|2025-09-09
Indexed document: Yes
Quartile: Q1
Keywords: Alpha power / Autism / Cingulate gyrus / Gamma power / Perception / Spatial frequency / Visual cortex

Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism

Independent component analysis reveals atypical EEG activity during visual perception in individuals with autism
DocumentMechanisms of speed encoding in the human middle temporal cortex measured by 7T fMRI2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2020
Location: BF-GMS
Title:
2020 Grants
Start date: 2021-01

Reference code: PT/FB/BL-2020-203
Location: BF-GMS
Title:
203 - Dynamic eye-movement encoding in human cortex using ultra-high field fMRI (7Tesla)
Duration: 2021-10 - 2023-09
Researcher(s):
Alessio Fracasso
Institution(s): Institute of Neuroscience and Psychology, University of Glasgow, Scotland (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Fracasso, A.
Number of reproductions:
1
Keywords:
Gain-field / Modelling / Saccades / Ultra high-field MRI / Psychophysiology

Reference code: PT/FB/BL-2020-203.10
Location: BF-GMS
Title:
Mechanisms of speed encoding in the human middle temporal cortex measured by 7T fMRI
Publication year: 2023
URL:
https://onlinelibrary.wiley.com/doi/10.1002/hbm.26193
Abstract/Results: ABSTRACT:
Perception of dynamic scenes in our environment results from the evaluation of visual features such as the fundamental spatial and temporal frequency components of a moving object. The ratio between these two components represents the object's speed of motion. The human middle temporal cortex hMT+ has a crucial biological role in the direct encoding of object speed. However, the link between hMT+ speed encoding and the spatiotemporal frequency components of a moving object is still under explored. Here, we recorded high resolution 7T blood oxygen level-dependent BOLD responses to different visual motion stimuli as a function of their fundamental spatial and temporal frequency components. We fitted each hMT+ BOLD response with a 2D Gaussian model allowing for two different speed encoding mechanisms: (1) distinct and independent selectivity for the spatial and temporal frequencies of the visual motion stimuli; (2) pure tuning for the speed of motion. We show that both mechanisms occur but in different neuronal groups within hMT+, with the largest subregion of the complex showing separable tuning for the spatial and temporal frequency of the visual stimuli. Both mechanisms were highly reproducible within participants, reconciling single cell recordings from MT in animals that have showed both encoding mechanisms. Our findings confirm that a more complex process is involved in the perception of speed than initially thought and suggest that hMT+ plays a primary role in the evaluation of the spatial features of the moving visual input.
Accessibility: Document exists in file
Language:
eng
Author:
Gaglianese, A.
Secondary author(s):
Fracasso, A., Fernandes, F. G., Harvey, B., Dumoulin, S. O., Petridou, N.
Document type:
Article
Number of reproductions:
1
Reference:
Gaglianese, A., Fracasso, A., Fernandes, F. G., Harvey, B., Dumoulin, S. O., & Petridou, N. (2023). Mechanisms of speed encoding in the human middle temporal cortex measured by 7T fMRI. Human Brain Mapping, 44(5), 2050-2061. https://doi.org/10.1002/hbm.26193
2-year Impact Factor: 3.5|2024
Times cited: 3|2025-09-26
Indexed document: Yes
Quartile: Q1
Keywords: 7T fMRI / Gaussian modelling / hMT + / Spatial frequency / Speed encoding / Visual motion

Mechanisms of speed encoding in the human middle temporal cortex measured by 7T fMRI

Mechanisms of speed encoding in the human middle temporal cortex measured by 7T fMRI