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File044 - Inducing and measuring plasticity in response control mechanisms in the human brain2017-102021-09

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-044
Location: BF-GMS
Title:
044 - Inducing and measuring plasticity in response control mechanisms in the human brain
Duration: 2017-10 - 2021-09
Researcher(s):
Alejandra Sel de Felipe, Matthew Rushworth
Institution(s): Department of Experimental Psychology, University of Oxford (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Sel, A.
Secondary author(s):
Rushworth, M.
Number of reproductions:
1
Keywords:
Cognitive control / Response inhibition / Cortical plasticity / Neurostimulation / Psychophysiology
DocumentFinal report - Inducing and measuring plasticity in response control mechanisms in the human brain2019

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2016
Location: BF-GMS
Title:
2016 Grants
Start date: 2017-01

Reference code: PT/FB/BL-2016-044
Location: BF-GMS
Title:
044 - Inducing and measuring plasticity in response control mechanisms in the human brain
Duration: 2017-10 - 2021-09
Researcher(s):
Alejandra Sel de Felipe, Matthew Rushworth
Institution(s): Department of Experimental Psychology, University of Oxford (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Author: Sel, A.
Secondary author(s):
Rushworth, M.
Number of reproductions:
1
Keywords:
Cognitive control / Response inhibition / Cortical plasticity / Neurostimulation / Psychophysiology

Reference code: PT/FB/BL-2016-044.01
Location: BF-GMS
Title:
Final report - Inducing and measuring plasticity in response control mechanisms in the human brain
Publication year: 2019
URL:
https://www.bial.com/media/3756/inducing-and-measuring-plasticity-in-response-control-mechanisms-in-the-human-brain.pdf
Abstract/Results: ABSTRACT:
In our day-to-day experiences consecutive courses of actions and thoughts need to be controlled to allow the execution of goal-directed actions. Action control is exerted through cortical action selection mechanisms in the prefrontal cortex that allow the selection or suppression of actions according to the environmental demands. The right inferior frontal cortex (rIFC) plays a pre-eminent and crucial role in action selection and inhibition in humans. The aim of the project was to investigate how the rIFC exerts its influence over action responses and whether this influence can be changed by inducing plasticity of the corticocortical pathways mediating response inhibition in the human brain. We performed 4 studies in which we investigated the influence of repetitive paired associative transcranial magnetic stimulation (repetitive ppTMS) on the corticocortical excitability and oscillatory dynamics of the rIFC-M1 pathway. In all four studies, participants performed a Go/Nogo task in two task blocks, baseline and expression. Between the baseline and the expression blocks, we applied the same paired associative stimulation (PAS) protocol at 0.1Hz for 15minutes, which is known to strengthen connectivity between pre-motor and motor cortex. The results of the studies 1 and 2 confirmed state-dependent changes in the motor-evoked potentials after the plasticity induction phase. In the go trials the paired PMv-M1 stimulation led to a facilitatory influence of PMv over M1. Additionally, the plasticity effect was dependent on stimulation order: repeated stimulation of PMv before M1 led to strengthening of the PMv–M1 pathway, while these effects were not present when M1 was stimulated before PMv. In parallel, the results of the studies 3 and 4 showed state-dependent changes in cortical oscillatory dynamics in the beta and theta frequencies, that were also dependent on stimulation order: repeated stimulation of PMv before M1 led to decreases in the beta band and increases in the theta band, whereas the opposite was true when stimulation of M1 preceded PMv stimulation.
Accessibility: Document exists in file
Language:
eng
Author:
Sel, A.
Document type:
Final report
Number of reproductions:
1
Reference:
Sel, A. (2018). Final report - Inducing and measuring plasticity in response control mechanisms in the human brain.
Indexed document: No
Keywords: Cognitive control / Response inhibition / Cortical plasticity / Neurostimulation

Final report - Inducing and measuring plasticity in response control mechanisms in the human brain

Final report - Inducing and measuring plasticity in response control mechanisms in the human brain
File204 - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway2019-032023-04

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-204
Location: BF-GMS
Title:
204 - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway
Duration: 2019-03 - 2023-04
Researcher(s):
Vincenzo Romei
Institution(s): Centre for studies and research in Cognitive Neuroscience - CsrNC, Department of Psychology, University of Bologna (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Romei, V.
Secondary author(s):
Poch, C.
Number of reproductions:
1
Keywords:
Brain oscillations / Working memory / Functional connectivity / Neurostimulation / Psychophysiology
DocumentThe cerebellum is causally involved in episodic memory under aging2023

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2014
Location: BF-GMS
Title:
2014 Grants
Start date: 2015-01

Reference code: PT/FB/BL-2014-495
Location: BF-GMS
Title:
495 - Episodic memory enhancement in aging: the role of cognitive training combined with (bilateral) tDCS in the medial-temporal cortex and cerebellum on episodic memory performance in the elderly
Duration: 2015-07 - 2022-03
Researcher(s):
Mário Manuel Rodrigues Simões, Felipe Fregni, Filipe Fernandes, Jorge Evandro de Araújo Alves, Marcel Simis, Ana Rita Simões Martins
Institution(s): CINEICC - Centro de Investigação do Núcleo de Estudos e Intervenção Cognitivo-Comportamental/Universidade de Coimbra (Portugal)
Contents: Contents:
Bursary agreement
Application form
Correspondence
Progress report
Final report
Article
Language: eng
Author:
Simões, M. R.
Secondary author(s):
Fregni, F., Fernandes, F., Alves, J. E., Simis, M.
Number of reproductions:
1
Keywords:
Memory decline assessment / Cognitive training / tDCS / Cerebellum / Psychophysiology

Reference code: PT/FB/BL-2014-495.07
Location: BF-GMS
Title:
The cerebellum is causally involved in episodic memory under aging
Publication year: 2023
URL:
https://link.springer.com/article/10.1007/s11357-023-00738-0
Abstract/Results: ABSTRACT:
Episodic memory decline is a major signature of both normal and pathological aging. Many neural regions have been implicated in the processes subserving both episodic memory and typical aging decline. Here, we demonstrate that the cerebellum is causally involved episodic memory under aging. We show that a 12-day neurostimulation program delivered to the right cerebellum led to improvements in episodic memory performance under healthy aging that long outlast the stimulation period — healthy elderly individuals show episodic memory improvement both immediately after the intervention program and in a 4-month follow-up. These results demonstrate the causal relevance of the cerebellum in processes associated with long-term episodic memory, potentially highlighting its role in regulating and maintaining cognitive processing. Moreover, they point to the importance of non-pharmacological interventions that prevent or diminish cognitive decline in healthy aging.
Accessibility: Document exists in file
Language:
eng
Author:
Almeida, J.
Secondary author(s):
Martins, A. R., Amaral, L., Valério, D., Bukhari, Q., Schu, G., Nogueira, J., Spínola, M., Soleimani, G., Fernandes, F., Silva, A. R., Fregni, F., Simis, M., Simões, M., Peres, A.
Document type:
Article
Number of reproductions:
1
Percentiles:
4
Reference:
Almeida, J., Martins, A. R., Amaral, L., Valério, D., Bukhari, Q., Schu, G., Nogueira, J., Spínola, M., Soleimani, G., Fernandes, F., Silva, A. R., Fregni, F., Simis, M., Simões, M., & Peres, A. (2023). The cerebellum is causally involved in episodic memory under aging. GeroScience, 45(4), 2267–2287. https://doi.org/10.1007/s11357-023-00738-0
2-year Impact Factor: 5.3|2023
Times cited: 2|2024-02-16
Indexed document: Yes
Quartile: Q1
Keywords: Episodic memory decline / Cerebellum / Neurostimulation

The cerebellum is causally involved in episodic memory under aging

The cerebellum is causally involved in episodic memory under aging
DocumentFinal report - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-204
Location: BF-GMS
Title:
204 - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway
Duration: 2019-03 - 2023-04
Researcher(s):
Vincenzo Romei
Institution(s): Centre for studies and research in Cognitive Neuroscience - CsrNC, Department of Psychology, University of Bologna (Italy)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Romei, V.
Secondary author(s):
Poch, C.
Number of reproductions:
1
Keywords:
Brain oscillations / Working memory / Functional connectivity / Neurostimulation / Psychophysiology

Reference code: PT/FB/BL-2018-204.01
Location: BF-GMS
Title:
Final report - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway
Publication year: 2022
Accessibility:
Document exists in file
Language:
eng
Document type:
Final report
Number of reproductions:
1
Reference:
Romei, V. (2023). Final report - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway.
Indexed document: No
Keywords: Working Memory / Hebbian plasticity / Brain oscillations / Frontoparietal connectivity / Neurostimulation

Final report - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway

Final report - Boosting WM capacity by strengthening the oscillatory functional fronto-parietal pathway
DocumentFinal report - The middle-age brain2022

Reference code: PT/FB
Entity holding: BIAL Foundation
Location: S. Mamede do Coronado
Title:
BIAL Foundation Archive
Start date: 1994
History:
The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives.
Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge.
Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research.
The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology.
To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world.
Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL: http://www.bial.com/pt/
Accessibility: By permission

Reference code: PT/FB/BL
Entity holding: BIAL Foundation
Title: BIAL Grants
Start date: 1994
History:
In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology.
Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries.
The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project.
The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665).
Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others.
The BIAL grants are promoted biannually.

Reference code: PT/FB/BL-2018
Location: BF-GMS
Title:
2018 Grants
Start date: 2019-01

Reference code: PT/FB/BL-2018-293
Location: BF-GMS
Title:
293 - The middle-age brain
Duration: 2019-03 - 2024-02
Researcher(s):
Marinella Cappelletti, Maria Herrojo Ruiz
Institution(s): Department of Psychology, Goldsmiths, University of London (UK)
Contents: Contents:
Application form
Correspondence
Research Funding Agreement
Progress report
Final report
Articles
Language: eng
Author:
Cappelletti, M.
Secondary author(s):
Herrojo Ruiz, M.
Number of reproductions:
1
Keywords:
Middle age / Brain oscillations / Cognitive abilities / Wellbeing / Psychophysiology

Reference code: PT/FB/BL-2018-293.01
Location: BF-GMS
Title:
Final report - The middle-age brain
Publication year: 2022
Abstract/Results:
ABSTRACT:
Background
Middle adulthood – the age between 40 and 60 – is characterised by many social, emotional, and health-related changes which mirror changes in brain and cognition. However, the neuroscience of the middle age brain is quite sparse, often due to the assumption that more informative brain changes are observed while growing up or ageing. However, identifying the roots of age-related changes earlier in adulthood may allow to minimise or prevent the cognitive, psychological and well-being issues that are often serious in late life.
Aims
To generate a novel, informed, and detailed profile of the middle-aged brain by studying the correlational and causal links between brain, cognitive functions, and well-being.
Method
A continuous measure of working memory performance as well as the source of errors typically affecting working memory was obtained in 179 adults across the life span (58 middle agers), in addition to information on well-being and cognitive reserve - a proxy for cognitive proficiency. In the same sample, data on parietal brain stimulation (tACS) in alpha, gamma, beta frequency or sham coupled with either the continuous working memory task or with a measure of time processing were also obtained. Electrophysiological (EEG) data were also collected, and analysed to identify resting state spectral power and the duration of burst events.
Results
Memory performance declined linearly with age, whereas changes in error rate peaked in middle age. At a physiological level, posterior alpha power – typically related to memory performance – as well as the ratio of long bursts within the upper alpha band changed linearly with age. In contrast, sensorimotor beta power and burst rate properties varied primarily non-linearly, with extrema during middle age. Hence, the initial increase in beta power and bursts during youth slowed in middle age reaching its maximum around the age of 60, and slowly decreased in older age. In parallel, memory performance following tACS to the posterior parietal regions changed non-linearly and was stimulation specific: there was a gamma-related working memory improvement in younger adults, a similar but alpha-related improvement in ageing participants, and a significant decline in middle agers following alpha-tACS. Time processing was instead specifically modulated by beta oscillations. Complementing these results, well-being indexes, and especially stress, were higher in middle agers and significantly reduced in those with higher cognitive reserve.
Conclusions
Ageing is characterized by distinct cognitive and well-being underlying patterns as well as different spatial and temporal brain dynamics, some critically arising or changing in middle age.
Accessibility: Document exists in file
Language:
eng
Author:
Cappelletti, M.
Document type:
Final report
Number of reproductions:
1
Reference:
Cappelletti, M. (2022). Final report - The middle-age brain.
Indexed document: No
Keywords: Middle age / Ageing / Brain oscillations / Parietal lobe / Working memory / Time processing / Neurostimulation

Final report - The middle-age brain

Final report - The middle-age brain