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Should salivettes be used to collect saliva for immunoglobulin A analysis?

2006

BIAL Foundation Archive
- BIAL Grants
  - 2004 Grants
    - 077 - Stress and the psyche: methodological innovations in psychoneuroimmunology
      - Should salivettes be used to collect saliva for immunoglobulin A analysis?

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2004
Location:	Arquivo PCA - Pastas 1 a 25/2004
Title:	2004 Grants
Start date:	2005-01 - 2012-09
Dimension/support:	25 caixas de arquivo

Reference code:	PT/FB/BL-2004-077
Location:	Arquivo PCA - Pasta 11/2004
Title:	077 - Stress and the psyche: methodological innovations in psychoneuroimmunology
Duration:	2005-03 - 2007-06
Researcher(s):	Matt Bristow, Rachel Cook
Institution(s):	Department of Psychology, APU, Cambridge (UK)
Contents:	Contents: Bursary agreement Application form Correspondence Financial report and expenditure documents Progress report Final report 3 unpublished documents (2 posters and 1 paper)
Language:	eng
Author:	Bristow, M.
Secondary author(s):	Cook, R.
Number of reproductions:	1
Keywords:	Psychophysiology / Stress and health / Psychoneuroimmunology / Endocrinology / Immunology / Assessment tools

Reference code:	PT/FB/BL-2004-077.02
Location:	Arquivo PCA - Pasta 11/2004
Title:	Should salivettes be used to collect saliva for immunoglobulin A analysis?
Publication year:	2006
Accessibility:	Document exists in file
Copyright/Reproduction:	By permission
Language:	eng
Author:	Bristow, M.
Secondary author(s):	Cook, R., Veerapen, S.
Document type:	Unpublished document
Number of reproductions:	1
Reference:	Bristow, M., Cook, R., & Veerapen, S. (2006). Should salivettes be used to collect saliva for immunoglobulin A analysis? [Unpublished document]
Indexed document:	No
Keywords:	Salivette / Immunoglobulin A / Protein / Salivary flow / Mucosal immunity / Psychoneuroimmunology
Should salivettes be used to collect saliva for immunoglobulin. A analysis?

Document

Should salivettes be used to collect saliva for Immunoglobulin A analysis?

2006

BIAL Foundation Archive
- BIAL Grants
  - 2004 Grants
    - 077 - Stress and the psyche: methodological innovations in psychoneuroimmunology
      - Should salivettes be used to collect saliva for Immunoglobulin A analysis?

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2004
Location:	Arquivo PCA - Pastas 1 a 25/2004
Title:	2004 Grants
Start date:	2005-01 - 2012-09
Dimension/support:	25 caixas de arquivo

Reference code:	PT/FB/BL-2004-077
Location:	Arquivo PCA - Pasta 11/2004
Title:	077 - Stress and the psyche: methodological innovations in psychoneuroimmunology
Duration:	2005-03 - 2007-06
Researcher(s):	Matt Bristow, Rachel Cook
Institution(s):	Department of Psychology, APU, Cambridge (UK)
Contents:	Contents: Bursary agreement Application form Correspondence Financial report and expenditure documents Progress report Final report 3 unpublished documents (2 posters and 1 paper)
Language:	eng
Author:	Bristow, M.
Secondary author(s):	Cook, R.
Number of reproductions:	1
Keywords:	Psychophysiology / Stress and health / Psychoneuroimmunology / Endocrinology / Immunology / Assessment tools

Reference code:	PT/FB/BL-2004-077.03
Location:	Arquivo PCA - Pasta 11/2004
Title:	Should salivettes be used to collect saliva for Immunoglobulin A analysis?
Publication year:	2006
URL:	http://abstracts.bps.org.uk/?&ResultsType=Abstracts&ResultSet_ID=1586&FormDisplayMode=view&frmShowSelected=true&localAction=details
Abstract/Results:	ABSTRACT: BACKGROUND: Salivettes (Sarstedt, UK) are a popular method of collecting saliva for measurement of IgA in psychoimmune research. It is a cause for concern that previous small-scale research suggests Salivettes reduce the level of IgA detected. This paper presents three studies that explore comprehensively the effects of Salivette use on the measurement of IgA and total protein in saliva. METHODS: In study I, 35 participants provided saliva using Salivettes and passive drooling in a counterbalanced design. In study II, 38 saliva samples were collected via passive drooling and filtered through the cotton wadding of a Salivette in order to directly test whether Salivettes alter the IgA concentration of saliva. Study III tested whether Salivettes leaked protein into the saliva. Three different volumes of saline were added to the Salivettes and the protein levels in the extracted saliva tested. FINDINGS: Study I and II both found that only around 50% of the variance in IgA from passively drooled saliva could be explained using the IgA concentrations from Salivette filtered IgA. Both studies also revealed a substantial reduction in IgA from Salivette filtered saliva. Study III showed that saline filtered through Salivettes acquired a substantial and - volume dependent – amount of total protein. DISCUSSION: A large amount of random error is introduced into the measurement of IgA and total protein in saliva extracted from Salivettes. This suggests Salivettes are not appropriate for collecting saliva for IgA and protein analysis, and researchers investigating psycho-immune relationships should carefully consider alternative methods for collection.
Accessibility:	Document exists in file (poster)
Copyright/Reproduction:	By permission
Language:	eng
Author:	Veerapen, S.
Secondary author(s):	Bristow, M., Cook, R.
Document type:	Online abstract
Number of reproductions:	1
Reference:	Veerapen, S., Bristow, M., & Cook, R. (2006, September). Should salivettes be used to collect saliva for Immunoglobulin A analysis? Poster presented at the BPS Health Psychology Annual Conference, Colchester, UK. Abstract retrieved from: http://abstracts.bps.org.uk/?&ResultsType=Abstracts&ResultSet_ID=1586&FormDisplayMode=view&frmShowSelected=true&localAction=details
Indexed document:	No
Keywords:	Salivette / Immunoglobulin A / Protein / Salivary flow / Mucosal immunity / Psychoneuroimmunology
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