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Meta-analytic evidence for a reversal learning effect on the Iowa gambling task in older adults

2017

BIAL Foundation Archive
- BIAL Foundation Other Grants
  - The Aging Social Brain – Neural and behavioral age-related changes in social cognition and decision-making
    - Meta-analytic evidence for a reversal learning effect on the Iowa gambling task in older adults

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Title:	BIAL Foundation Other Grants

Reference code:	Aging
Location:	Arquivo PCA - Pasta 1/Outros Apoios
Title:	The Aging Social Brain – Neural and behavioral age-related changes in social cognition and decision-making
Duration:	2014-11 - 2018-01
Researcher(s):	João Eduardo Marques Teixeira, Manuel Fernando Santos Barbosa, Fernando Ricardo Ferreira Santos, Pedro Manuel Rocha Almeida, Hugo Daniel Leão Sousa
Institution(s):	Faculdade de Psicologia e de Ciências da Educação, Universidade do Porto, Portugal
Contents:	Application Research Funding Agreement Progress report Final report Submitted and published articles
Language:	por / eng
Author:	Marques-Teixeira, J.
Secondary author(s):	Barbosa, F., Ferreira-Santos, F., Almeida, P. R., Sousa. H.
Number of reproductions:	1
Keywords:	Psychophysiology / Emotional processing / Empathy / Theory of mind / Moral judgement / Decision making / Aging

Reference code:	Aging-06
Location:	Arquivo PCA - Pasta 1/Outros Apoios
Title:	Meta-analytic evidence for a reversal learning effect on the Iowa gambling task in older adults
Publication year:	2017
URL:	https://www.frontiersin.org/articles/10.3389/fpsyg.2017.01785/full
Abstract/Results:	ABSTRACT: Iowa Gambling Task (IGT) is one of the most widely used tools to assess economic decision-making. However, the research tradition on aging and the Iowa Gambling Task (IGT) has been mainly focused on the overall performance of older adults in relation to younger or clinical groups, remaining unclear whether older adults are capable of learning along the task. We conducted a meta-analysis to examine older adults' decision-making on the IGT, to test the effects of aging on reversal learning (45 studies) and to provide normative data on total and block net scores (55 studies). From the accumulated empirical evidence, we found an average total net score of 7.55 (±25.9). We also observed a significant reversal learning effect along the blocks of the IGT, indicating that older adults inhibit the prepotent response toward immediately attractive options associated with high losses, in favor of initially less attractive options associated with long-run profit. During block 1, decisions of older adults led to a negative gambling net score, reflecting the expected initial pattern of risk-taking. However, the shift toward more safe options occurred between block 2 (small-to-medium effect size) and blocks 3, 4, 5 (medium-to-large effect size). These main findings highlight that older adults are able to move from the initial uncertainty, when the possible outcomes are unknown, to decisions based on risk, when the outcomes are learned and may be used to guide future adaptive decision-making.
Accessibility:	Document exists in file
Language:	eng
Author:	Passion, R.
Secondary author(s):	Gonçalves, G., Fernandes, C., Ferreira-Santos, F., Barbosa, F., Marques-Teixeira, J.
Document type:	Article
Number of reproductions:	1
Reference:	Passion, R., Gonçalves, G., Fernandes, C., Ferreira-Santos, F., Barbosa, F., & Marques-Teixeira, J. (2017). Meta-analytic evidence for a reversal learning effect on the Iowa gambling task in older adults. Frontiers in Psychology, 8: 1785. https://doi.org/10.3389/fpsyg.2017.01785
2-year Impact Factor:	2.089\|2017
Times cited:	15\|2025-02-11
Indexed document:	Yes
Quartile:	Q2
Keywords:	Iowa Gambling Task / Decision-making / Risk / Uncertainty / Aging / Older adults / Neuropsychology
Meta-analytic evidence for a reversal learning effect on the Iowa gambling task in older adults

Document

Final report - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults

2019

BIAL Foundation Archive
- BIAL Grants
  - 2016 Grants
    - 032 - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults
      - Final report - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2016
Location:	BF-GMS
Title:	2016 Grants
Start date:	2017-01

Reference code:	PT/FB/BL-2016-032
Location:	BF-GMS
Title:	032 - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults
Duration:	2017-04 - 2019-09
Researcher(s):	Serena Scarpelli, Luigi De Gennaro, Anastasia Mangiaruga, Chiara Bartolacci
Institution(s):	Department of Psychology, University of Rome “La Sapienza” (Italy)
Contents:	Contents: Application form Correspondence Research Funding Agreement Progress report Final report Articles
Author:	Scarpeli, S.
Secondary author(s):	De Gennaro, L., Mangiaruga, A., Bartolacci, C.
Number of reproductions:	1
Keywords:	Dream recall / Aging / Electroencephalogram (EEG) / Oscillatory activity / Psychophysiology

Reference code:	PT/FB/BL-2016-032.01
Location:	BF-GMS
Title:	Final report - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults
Publication year:	2019
Abstract/Results:	ABSTRACT BACKGROUND Neural correlates of dream recall (DR) in elderly people are still largely unknown. Previous studies in older adults found a general decrease in DR and with the notable exception of Chellappa et al. (2009) no investigations have been carried out on EEG correlates of DR in aging. AIM Our study aimed to investigate whether specific EEG patterns during sleep in elderly predict a subsequent DR. Method: 40 healthy older and 40 young adults were recorded with polysomnography: 21 older subjects were awakened from REM sleep and 19 older subjects from stage 2 NREM sleep; 20 young subjects were awakened from REM sleep and 20 young subjects from stage 2. DRs were collected upon morning awakening from both stages. EEG power spectra of the total sleep and of the last 5 min were calculated by Fast Fourier Transform (FFT). The algorithm to detect oscillatory activity was applied on the last 5 min of sleep. RESULTS The two-way ANOVAs Recall X Age performed on the EEG power bands showed no main effect of Recall neither significant interaction for REM sleep as well as NREM sleep. Only a significant main effect of Age was observed both for total sleep and the last 5 min, during REM and NREM sleep. The analysis of oscillatory activity revealed that frontal theta oscillations during the last 5 min of REM sleep are related to DR, without any age-effect. CONCLUSIONS Our result replicated the previous evidence in young subjects and it is completely new for older individuals, showing that the theta oscillations play a pivotal role in the retrieval of dreaming also in this population. The findings are in line with the Continuity Hypothesis between waking and sleep mental functioning from a neurobiological viewpoint.
Accessibility:	Document exists in file
Language:	eng
Author:	Scarpelli, S.
Secondary author(s):	De Gennaro, L., Mangiaruga, A., Bartolacci, C.
Document type:	Final report
Number of reproductions:	1
Indexed document:	No
Keywords:	Dream recall / Dreaming / EEG / Older adults / REM sleep / NREM sleep / Theta oscillations
Final report - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults

Document

Oscillatory EEG activity during REM sleep in elderly people predicts subsequent dream recall after awakenings

2019

BIAL Foundation Archive
- BIAL Grants
  - 2016 Grants
    - 032 - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults
      - Oscillatory EEG activity during REM sleep in elderly people predicts subsequent dream recall after awakenings

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2016
Location:	BF-GMS
Title:	2016 Grants
Start date:	2017-01

Reference code:	PT/FB/BL-2016-032
Location:	BF-GMS
Title:	032 - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults
Duration:	2017-04 - 2019-09
Researcher(s):	Serena Scarpelli, Luigi De Gennaro, Anastasia Mangiaruga, Chiara Bartolacci
Institution(s):	Department of Psychology, University of Rome “La Sapienza” (Italy)
Contents:	Contents: Application form Correspondence Research Funding Agreement Progress report Final report Articles
Author:	Scarpeli, S.
Secondary author(s):	De Gennaro, L., Mangiaruga, A., Bartolacci, C.
Number of reproductions:	1
Keywords:	Dream recall / Aging / Electroencephalogram (EEG) / Oscillatory activity / Psychophysiology

Reference code:	PT/FB/BL-2016-032.08
Location:	BF-GMS
Title:	Oscillatory EEG activity during REM sleep in elderly people predicts subsequent dream recall after awakenings
Publication year:	2019
URL:	https://www.frontiersin.org/articles/10.3389/fneur.2019.00985/full
Abstract/Results:	ABSTRACT Several findings underlined that the electrophysiological (EEG) background of the last segment of sleep before awakenings may predict the presence/absence of dream recall (DR) in young subjects. However, little is known about the EEG correlates of DR in elderly people. Only an investigation found differences between recall and non-recall conditions during NREM sleep EEG in older adults, while—surprisingly—no EEG predictor of DR was found for what concerns REM sleep. Considering REM sleep as a privileged scenario to produce mental sleep activity related to cognitive processes, our study aimed to investigate whether specific EEG topography and frequency changes during REM sleep in elderly people may predict a subsequent recall of mental sleep activity. Twenty-one healthy older volunteers (mean age 69.2 ± 6.07 SD) and 20 young adults (mean age 23.4 ± 2.76 SD) were recorded for one night from 19 scalp derivations. Dreams were collected upon morning awakenings from REM sleep. EEG signals of the last 5 min were analyzed by the Better OSCillation algorithm to detect the peaks of oscillatory activity in both groups. Statistical comparisons revealed that older as well as young individuals recall their dream experience when the last segment of REM sleep is characterized by frontal theta oscillations. No Recall (Recall vs. Non-Recall) × Age (Young vs. Older) interaction was found. This result replicated the previous evidence in healthy young subjects, as shown in within- and between-subjects design. The findings are completely original for older individuals, demonstrating that theta oscillations are crucial for the retrieval of dreaming also in this population. Furthermore, our results did not confirm a greater presence of the theta activity in healthy aging. Conversely, we found a greater amount of rhythmic theta and alpha activity in young than older participants. It is worth noting that the theta oscillations detected are related to cognitive functioning. We emphasize the notion that the oscillatory theta activity should be distinguished from the non-rhythmic theta activity identified in relation to other phenomena such as (a) sleepiness and hypoarousal conditions during the waking state and (b) cortical slowing, considered as an EEG alteration in clinical samples.
Accessibility:	Document exists in file
Language:	eng
Author:	Scarpelli, S.
Secondary author(s):	D'Atri, A., Bartolacci, C., Mangiaruga, A., Gorgoni, M., De Gennaro, L.
Document type:	Article
Number of reproductions:	1
Reference:	Scarpelli, S., D'Atri, A., Bartolacci, C., Mangiaruga, A., Gorgoni, M., & De Gennaro, L. (2019). Oscillatory EEG activity during REM sleep in elderly people predicts subsequent dream recall after awakening. Frontiers in Neurology, 10, 985. https://doi.org/10.3389/fneur.2019.00985
2-year Impact Factor:	2.889\|2019
Times cited:	15\|2025-02-13
Indexed document:	Yes
Quartile:	Q2
Keywords:	Dream recall / Dreaming / Elderly / Older adults / Theta oscillations / REM sleep / EEG / Oscillatory activity
Oscillatory EEG activity during REM sleep in elderly people predicts subsequent dream recall after awakenings

Document

Dream recall upon awakening from non-rapid eye movement sleep in older adults: Electrophysiological pattern and qualitative features

2020

BIAL Foundation Archive
- BIAL Grants
  - 2016 Grants
    - 032 - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults
      - Dream recall upon awakening from non-rapid eye movement sleep in older adults: Electrophysiological pattern and qualitative features

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2016
Location:	BF-GMS
Title:	2016 Grants
Start date:	2017-01

Reference code:	PT/FB/BL-2016-032
Location:	BF-GMS
Title:	032 - Neural mechanisms of dream recall: Electrophysiological differences between young and older adults
Duration:	2017-04 - 2019-09
Researcher(s):	Serena Scarpelli, Luigi De Gennaro, Anastasia Mangiaruga, Chiara Bartolacci
Institution(s):	Department of Psychology, University of Rome “La Sapienza” (Italy)
Contents:	Contents: Application form Correspondence Research Funding Agreement Progress report Final report Articles
Author:	Scarpeli, S.
Secondary author(s):	De Gennaro, L., Mangiaruga, A., Bartolacci, C.
Number of reproductions:	1
Keywords:	Dream recall / Aging / Electroencephalogram (EEG) / Oscillatory activity / Psychophysiology

Reference code:	PT/FB/BL-2016-032.09
Location:	BF-GMS
Title:	Dream recall upon awakening from non-rapid eye movement sleep in older adults: Electrophysiological pattern and qualitative features
Publication year:	2020
URL:	https://www.mdpi.com/2076-3425/10/6/343/htm
Abstract/Results:	ABSTRACT: Several findings support the activation hypothesis, positing that cortical arousal promotes dream recall (DR). However, most studies have been carried out on young participants, while the electrophysiological (EEG) correlates of DR in older people are still mostly unknown. We aimed to test the activation hypothesis on 20 elders, focusing on the Non-Rapid Eye Movement (NREM) sleep stage. All the subjects underwent polysomnography, and a dream report was collected upon their awakening from NREM sleep. Nine subjects were recallers (RECs) and 11 were non-RECs (NRECs). The delta and beta EEG activity of the last 5 min and the total NREM sleep was calculated by Fast Fourier Transform. Statistical comparisons (RECs vs. NRECs) revealed no differences in the last 5 min of sleep. Significant differences were found in the total NREM sleep: the RECs showed lower delta power over the parietal areas than the NRECs. Consistently, statistical comparisons on the activation index (delta/beta power) revealed that RECs showed a higher level of arousal in the fronto-temporal and parieto-occipital regions than NRECs. Both visual vividness and dream length are positively related to the level of activation. Overall, our results are consistent with the view that dreaming and the storage of oneiric contents depend on the level of arousal during sleep, highlighting a crucial role of the temporo-parietal-occipital zone.
Accessibility:	Document exists in file
Language:	eng
Author:	Scarpelli, S.
Secondary author(s):	D’Atri, A., Bartolacci, C., Gorgoni, M., Mangiaruga, A., Ferrara, M., De Gennaro, L.
Document type:	Article
Number of reproductions:	1
Reference:	Scarpelli, S., D’Atri, A., Bartolacci, C., Gorgoni, M., Mangiaruga, A., Ferrara, M., & De Gennaro, L. (2020). Dream recall upon awakening from non-rapid eye movement sleep in older adults: Electrophysiological pattern and qualitative features. Brain Sciences, 10, 343. https://doi.org/10.3390/brainsci10060343
2-year Impact Factor:	3.394\|2020
Times cited:	20\|2025-02-14
Indexed document:	Yes
Quartile:	Q3
Keywords:	Dream recall / Dream report / Older adults / NREM sleep / EEG / Activation hypothesis / Delta / Beta
Dream recall upon awakening from non-rapid eye movement sleep in older adults: Electrophysiological pattern and qualitative features

Document

Working memory training coupled with transcranial direct current stimulation in older adults: A randomized controlled experiment

2022

BIAL Foundation Archive
- BIAL Grants
  - 2016 Grants
    - 286 - Getting the aging brain to train: A working memory and neurostimulation approach
      - Working memory training coupled with transcranial direct current stimulation in older adults: A randomized controlled experiment

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2016
Location:	BF-GMS
Title:	2016 Grants
Start date:	2017-01

Reference code:	PT/FB/BL-2016-286
Location:	BF-GMS
Title:	286 - Getting the aging brain to train: A working memory and neurostimulation approach
Duration:	2017-06 - 2023-03
Researcher(s):	Adriana Sampaio, Ana Teixeira Santos, Sandra Carvalho, Jorge Leite, Ana Raquel, Felipe Fregni
Institution(s):	Psychology Research Center (CIPsi), School of Psychology, University of Minho, Braga (Portugal); Spaulding-Labuschange Neuromodulation Center, Spaulding Rehabilitation Hospital & Massachusetts General Hospital/Harvard Medical School, Charlestown (USA)
Contents:	Contents: Application form Correspondence Research Funding Agreement Progress report Final report Articles
Author:	Sampaio, A.
Secondary author(s):	Teixeira-Santos, A. C., Carvalho, S., Leite, J., Mesquita, A. R., Fregni, F.
Number of reproductions:	1
Keywords:	Working memory training / Aging / Brain plasticity / Cognitive plasticity / Psychophysiology

Reference code:	PT/FB/BL-2016-286.05
Location:	BF-GMS
Title:	Working memory training coupled with transcranial direct current stimulation in older adults: A randomized controlled experiment
Publication year:	2022
URL:	https://www.frontiersin.org/articles/10.3389/fnagi.2022.827188/full
Abstract/Results:	Background: Transcranial direct current stimulation (tDCS) has been employed to boost working memory training (WMT) effects. Nevertheless, there is limited evidence on the efficacy of this combination in older adults. The present study is aimed to assess the delayed transfer effects of tDCS coupled with WMT in older adults in a 15-day follow-up. We explored if general cognitive ability, age, and educational level predicted the effects. Methods: In this single-center, double-blind randomized sham-controlled experiment, 54 older adults were randomized into three groups: anodal-tDCS (atDCS)+WMT, sham-tDCS (stDCS)+WMT, and double-sham. Five sessions of tDCS (2 mA) were applied over the left dorsolateral prefrontal cortex (DLPFC). Far transfer was measured by Raven’s Advanced Progressive Matrices (RAPM), while the near transfer effects were assessed through Digit Span. A frequentist linear mixed model (LMM) was complemented by a Bayesian approach in data analysis. Results: Working memory training improved dual n-back performance in both groups submitted to this intervention but only the group that received atDCS+WMT displayed a significant improvement from pretest to follow-up in transfer measures of reasoning (RAPM) and short-term memory (forward Digit Span). Near transfer improvements predicted gains in far transfer, demonstrating that the far transfer is due to an improvement in the trained construct of working memory. Age, formal education, and vocabulary score seem to predict the gains in reasoning. However, Bayesian results do not provide substantial evidence to support this claim. Conclusion: This study will help to consolidate the incipient but auspicious field of cognitive training coupled with tDCS in healthy older adults. Our findings demonstrated that atDCS may potentialize WMT by promoting transfer effects in short-term memory and reasoning in older adults, which are observed especially at follow-up.
Accessibility:	Document exists in file
Language:	eng
Author:	Teixeira-Santos, A. C.
Secondary author(s):	Moreira, C., Pereira, D., Pinal, D., Fregni, F., Leite, J., Carvalho, S., Sampaio, A.
Document type:	Article
Number of reproductions:	1
Reference:	Teixeira-Santos, A. C., Moreira, C., Pereira, D., Pinal, D., Fregni, F., Leite, J., Carvalho, S. & Sampaio, A. (2022). Working memory training coupled with transcranial direct current stimulation in older adults: A randomized controlled experiment. Frontiers in Aging Neuroscience, 14, 827188. https://doi.org/10.3389/fnagi.2022.827188
2-year Impact Factor:	4.800\|2022
Times cited:	13\|2025-02-17
Indexed document:	Yes
Quartile:	Q2
Keywords:	tDCS / Cognitive training / Working memory / Neuroplasticity / Older adults / Reasoning / Transfer effects
Working memory training coupled with transcranial direct current stimulation in older adults: A randomized controlled experiment

Document

Working memory and neuroplasticity in older people: A behavioral and neurofunctional approach

2020

BIAL Foundation Archive
- BIAL Grants
  - 2016 Grants
    - 286 - Getting the aging brain to train: A working memory and neurostimulation approach
      - Working memory and neuroplasticity in older people: A behavioral and neurofunctional approach

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2016
Location:	BF-GMS
Title:	2016 Grants
Start date:	2017-01

Reference code:	PT/FB/BL-2016-286
Location:	BF-GMS
Title:	286 - Getting the aging brain to train: A working memory and neurostimulation approach
Duration:	2017-06 - 2023-03
Researcher(s):	Adriana Sampaio, Ana Teixeira Santos, Sandra Carvalho, Jorge Leite, Ana Raquel, Felipe Fregni
Institution(s):	Psychology Research Center (CIPsi), School of Psychology, University of Minho, Braga (Portugal); Spaulding-Labuschange Neuromodulation Center, Spaulding Rehabilitation Hospital & Massachusetts General Hospital/Harvard Medical School, Charlestown (USA)
Contents:	Contents: Application form Correspondence Research Funding Agreement Progress report Final report Articles
Author:	Sampaio, A.
Secondary author(s):	Teixeira-Santos, A. C., Carvalho, S., Leite, J., Mesquita, A. R., Fregni, F.
Number of reproductions:	1
Keywords:	Working memory training / Aging / Brain plasticity / Cognitive plasticity / Psychophysiology

Reference code:	PT/FB/BL-2016-286.06
Location:	BF-GMS
Title:	Working memory and neuroplasticity in older people: A behavioral and neurofunctional approach
Publication year:	2020
URL:	https://repositorium.sdum.uminho.pt/handle/1822/76490
Abstract/Results:	ABSTRACT: Working memory training (WMT) has been used to promote neuroplasticity in older people and tDCS has been proposed to boost WMT effects. Nevertheless, there is not robust evidence of WMT effectiveness and the few studies assessing the combination of tDCS with WMT used cognitive tasks as endpoints. However, the use of different markers, as the event-related potentials (ERPs), can be useful to better understand the combined or individual effects of these interventions. Thus, the studies presented in this dissertation aimed to assess WMT effects, as well as, the add-on effects of tDCS. Given the need to use different endpoints to measures WMT-induced neuroplasticity, an additional aim was to assess if the ERPs can be used as indexes of fluid intelligence (Gf), a commonly assessed constructed to infer generalization of WMT. In the first study, we presented a meta-analysis on the effects of WMT in healthy elderly. Small significant and long-lasting gains were observed in working memory (WM), but not in short-term memory (STM) and Gf tasks. Type of training tasks, the adopted outcome measures, the training duration, and the total number of training hours moderated WMT effects. In the second study, we performed a systematic review on the uses of tDCS to boost WM in healthy older adults. The studies suggest that tDCS may modulate WM in this population, improving the accuracy and shortening the reaction time. In the third study, we performed a randomized double-blind controlled experiment to evaluate the effects of 5-day WMT coupled with tDCS in healthy older adults. Fifty-four participants were assigned to one of three groups: 1) WMT (dual n-back task)+active tDCS (atDCS); 2) WMT+sham tDCS (stDCS); or 3) sham task + sham tDCS. During the training, both groups that performed the dual n-back task (WMT+atDCS; WMT+stDCS) improved throughout sessions, with no significant differences between them. However, the “WMT+atDCS” was the only group that presented gains in Gf and verbal STM after training (i.e., next day after the intervention) and at follow-up (i.e., 15 days follow-up). Finally, in the fourth study, we explored whether ERP components (i.e., P2, P3b and the LPC - late positive complex) are associated with Gf in the elderly. Fifty-seven participants performed a continuous performance task and a visual oddball paradigm while EEG was recorded. They were divided into high-performance (HP) and low performance (LP) groups according to their performance in the Raven’s Advanced Progressive Matrices test (RAPM). HP group presented significant higher LPC amplitudes in the CPT and shorter P3b latencies in the oddball task when compared to the LP group.
Accessibility:	Document exists in file
Language:	eng
Author:	Teixeira-Santos, A. C.
Document type:	Doctoral thesis
Number of reproductions:	1
Reference:	Teixeira-Santos, A. C. (2020). Working memory and neuroplasticity in older people: A behavioral and neurofunctional approach (Doctoral thesis in Basic Psychology, Escola de Psicologia, Universidade do Minho, Braga, Portugal). Retrieved at: https://repositorium.sdum.uminho.pt/handle/1822/76490
Indexed document:	No
Keywords:	Fluid intelligence / Late positive complex / Older adults / P3b / tDCS / Working memory training
Working memory and neuroplasticity in older people: A behavioral and neurofunctional approach

Document

Cognitive, psychological, and physiological effects of a web-based mindfulness intervention in older adults during the COVID-19 pandemic: an open study

2024

BIAL Foundation Archive
- BIAL Grants
  - 2018 Grants
    - 104 - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly
      - Cognitive, psychological, and physiological effects of a web-based mindfulness intervention in older adults during the COVID-19 pandemic: an open study

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2018
Location:	BF-GMS
Title:	2018 Grants
Start date:	2019-01

Reference code:	PT/FB/BL-2018-104
Location:	BF-GMS
Title:	104 - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly
Duration:	2019-02 - 2024-02
Researcher(s):	Samantha Galluzzi, Davide Moretti, Mariangela Lanfredi, Laura Pedrini, Roberta Rossi
Institution(s):	IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia (Italy)
Contents:	Contents: Application form Correspondence Research Funding Agreement Progress report Final report Articles
Language:	eng
Author:	Galluzzi, S.
Secondary author(s):	Moretti, D., Lanfredi, M., Pedrini, L., Rossi, R.
Number of reproductions:	3
Keywords:	Mindfulness / Electroencephalography / Elderly / Well-being / Psychophysiology and Parapsychology

Reference code:	PT/FB/BL-2018-104.03
Location:	BF-GMS
Title:	Cognitive, psychological, and physiological effects of a web-based mindfulness intervention in older adults during the COVID-19 pandemic: an open study
Publication year:	2024
URL:	https://doi.org/10.1186/s12877-024-04766-z
Abstract/Results:	ABSTRACT: Background The development of effective strategies to maintain good mental health of older adults is a public health priority. Mindfulness-based interventions have the potential to improve psychological well-being and cognitive functions of older adults, but little is known about the effect of such interventions when delivered through internet. During the COVID-19 pandemic we evaluated short- and long-term cognitive, psychological, and physiological effects of a mindfulness-based intervention (MBI) delivered via web-based videoconference in healthy older adults. Methods Fifty older adults participated in an 8-week MBI, which comprised structured 2-h weekly group sessions. A comprehensive evaluation encompassing cognitive (verbal memory, attention and processing speed, executive functions) and psychological assessments (depression and anxiety symptoms, mindfulness, worries, emotion regulation strategies, well-being, interoceptive awareness and sleep) was conducted. Additionally, electroencephalography (EEG) data were recorded before and after the MBI and at the 6-month follow-up (T6). Data were analyzed using an intention-to-treat approach, using linear mixed models adjusted for age. The effect size for time was computed as omega squared. Results We observed significant improvements from pre-MBI to post-MBI and at the T6 across several measures. These improvements were notable in the areas of verbal memory (California Verbal Learning Test, p = .007), attention and executive functions (Trail Making Test A and BA, p < .050), interoceptive awareness (Multidimensional Assessment of Interoceptive Awareness, p = .0002 for self-regulation and p < .05 for noticing, body listening, and trusting dimensions), and rumination (Heidelberg Form for Emotion Regulation Strategies, p = .018). These changes were associated with low to medium effect size. Moreover, we observed significant changes in EEG patterns, with a decrease in alpha1 (p = .004) and an increase in alpha2 (p < .0001) from pre-MBI to T6. Notably, improvements in TMTBA and rumination were correlated with the decrease in alpha1 (p < .050), while improvements in TMTA were linked to the increase in alpha2 (p = .025). Conclusions The results of our study show that a web-based MBI in older adults leads to improvements in cognitive and psychological measures, with associated modulations in specific brain rhythms. While these findings are promising, further controlled studies are required to validate these preliminary results. Trial registration The trial has been registered with the United States National Library of Medicine at the National Institutes of Health Registry of Clinical Trials under the code NCT05941143 on July 12, 2023.
Accessibility:	Document exists in file
Language:	eng
Author:	Galluzzi, S.
Secondary author(s):	Lanfredi, M., Moretti, D. V., Rossi, R., Meloni, S., Tomasoni, E., Frisoni, G. B., Chiesa, A., Pievani, M.
Document type:	Article
Number of reproductions:	1
Reference:	Galluzzi, S., Lanfredi, M., Moretti, D. V., Rossi, R., Meloni, S., Tomasoni, E., Frisoni, G. B., Chiesa, A., & Pievani, M. (2024). Cognitive, psychological, and physiological effects of a web-based mindfulness intervention in older adults during the COVID-19 pandemic: an open study. BMC geriatrics, 24(1), 151. https://doi.org/10.1186/s12877-024-04766-z
2-year Impact Factor:	3.4\|2023
Impact factor notes:	Impact factor not available yet for 2024
Times cited:	1\|2025-02-19
Indexed document:	Yes
Quartile:	Q2
Keywords:	Older adults / Mindfulness / Web videoconference / Cognitive / Psychological / Electroencephalogram (EEG)
Cognitive, psychological, and physiological effects of a web-based mindfulness intervention in older adults during the COVID-19 pandemic: an open study

Document

Final report - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly

2023

BIAL Foundation Archive
- BIAL Grants
  - 2018 Grants
    - 104 - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly
      - Final report - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly

Reference code:	PT/FB
Entity holding:	BIAL Foundation
Location:	S. Mamede do Coronado
Title:	BIAL Foundation Archive
Start date:	1994
History:	The BIAL Foundation was created in 1994 by Laboratórios BIAL in conjunction with the Council of Rectors of Portuguese Universities. BIAL’s Foundation mission is to foster the scientific study of Man from both the physical and spiritual perspectives. Along the years the BIAL Foundation has developed an important relationship with the scientific community, first in Portugal and after worldwide. Today it is an institution of reference which aims to stimulate new researches that may help people, promote more health and contribute to new milestones to gain access to knowledge. Among its activities the BIAL Foundation manages the BIAL Award, created in 1984, one of the most important awards in the Health field in Europe. The BIAL Award rewards both the basic and the clinical research distinguishing works of major impact in medical research. The BIAL Foundation also assigns Scientific Research Scholarships for the study of neurophysiological and mental health in people, arousing the interest of researchers in the areas of Psychophysiology and Parapsychology. To date the BIAL Foundation has supported 461 projects, more than 1000 researchers, with research groups in twenty-seven countries, resulting, until April 2013, in about 600 full papers, out of which 172 published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Since 1996 the BIAL Foundation organizes the Symposia entitled "Behind and Beyond the Brain", a Forum that gathers well renowned neurosciences speakers and the BIAL Foundation Fellows which are spread around the world. Classified as an institution of public utility, the BIAL Foundation includes among its patrons the Portuguese President, the Portuguese Universities Rectors' Council and the Portuguese Medical Association.
URL:	http://www.bial.com/pt/
Accessibility:	By permission

Reference code:	PT/FB/BL
Entity holding:	BIAL Foundation
Title:	BIAL Grants
Start date:	1994
History:	In 1994 the BIAL Foundation launched a programme of science research grants with the aim of encouraging the research into Man’s physical and mental processes, namely in fields still largely unexplored but which warrant further scientific analysis, as Psychophysiology and Parapsychology. Since its launch, applications to the BIAL grants have been increasing. Up to now 461 projects have been supported, involving more than 1000 researchers from 27 countries. The approved applications have benefited from grants in amounts comprised between €5,000 and €50, 000. The amount to be granted is fixed by the Scientific board according to the needs of each project. The supported projects have originated, until April 2013, in about 600 full papers, 172 out of which were published in indexed international journals with an average impact factor of 3.6 and a substantial number of citations (1665). Among the BIAL Foundation fellows is worth highlighting the presence of scientists from prestigious universities from the United States, United Kingdom, Australia, Russia, Germany, Japan, France, Canada, and many others. The BIAL grants are promoted biannually.

Reference code:	PT/FB/BL-2018
Location:	BF-GMS
Title:	2018 Grants
Start date:	2019-01

Reference code:	PT/FB/BL-2018-104
Location:	BF-GMS
Title:	104 - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly
Duration:	2019-02 - 2024-02
Researcher(s):	Samantha Galluzzi, Davide Moretti, Mariangela Lanfredi, Laura Pedrini, Roberta Rossi
Institution(s):	IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia (Italy)
Contents:	Contents: Application form Correspondence Research Funding Agreement Progress report Final report Articles
Language:	eng
Author:	Galluzzi, S.
Secondary author(s):	Moretti, D., Lanfredi, M., Pedrini, L., Rossi, R.
Number of reproductions:	3
Keywords:	Mindfulness / Electroencephalography / Elderly / Well-being / Psychophysiology and Parapsychology

Reference code:	PT/FB/BL-2018-104.01
Location:	BF-GMS
Title:	Final report - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly
Publication year:	2023
Abstract/Results:	ABSTRACT: Background As the worldwide population of older adults is rapidly increasing, effective strategies are needed to maintain cognitive and psychological well-being. Aims To evaluate if cognitive and psychological well-being and their neurophysiological correlates may be modulated by mindfulness training (MT) in healthy older adults. Method Seventy older adults took part in a standardized MT program consisting of 8 weekly group 2-hour sessions, delivered in-person (n=20) or via web-based videoconference (n=50). A comprehensive cognitive (verbal memory, attention and executive functions) and psychological (anxious and depressive symptoms, dispositional mindfulness, worries, emotion regulation strategies, wellbeing, interoceptive awareness, sleep) evaluation and EEG recording were collected at pre- and post-MT and at 6-month follow-up. Results n the online sample (n=50), we found a significant effect of time on verbal memory, attention switching and executive functions, interoceptive awareness, and rumination (p<.05). EEG alpha1 significantly decreased (p=.005) and alpha2 significantly increased (p<.0001) from pre-MT to post-MT and T6. Significant correlations between cognitive measures and EEG variables were found (p<.05). In the online and in-person sample (n=52) divided by presence (n=30) or absence (n=22) of subjective cognitive decline (SCD), older adults with SCD improved on cognitive and psychological measures, with a divergent effect on dispositional mindfulness and interoceptive awareness relative to no-SCD (p<.05). Conclusions Web-based MT improves cognitive and psychological measures in older adults by modulating neural activity in specific brain rhythms. Controlled studies are needed to confirm these results.
Accessibility:	Document exists in file
Language:	eng
Author:	Galluzzi, S.
Secondary author(s):	Moretti, D., Lanfredi, M., Pedrini, L., Rossi, R.
Document type:	Final report
Number of reproductions:	1
Reference:	Galluzzi, S., Moretti, D., Lanfredi, M., Pedrini, L., & Rossi, R. (2023). Final report - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly.
Indexed document:	No
Keywords:	Mindfulness training / Older adults / Web videoconference / Cognitive / Psychological / Electroencephalogram (EEG)
Final report - Effect of mindfulness on EEG brain activity for cognitive and psychological well-being in the elderly